Vitamin D Deficiency

Nearly 50 percent of people worldwide are deficient in Vitamin D. This number is higher amongst those of us who live in more northern climates. Vitamin D, or the sunshine vitamin, is actually a steroid hormone that our bodies make in response to ultraviolet light (UVB specifically). 

The UVB rays from sunlight trigger the production of Vitamin D3 (cholecalciferol) in our skin. This compound must then go through additional steps in both the liver and kidneys to become the active form of vitamin D3, which is calcitriol. Being able to manufacture our own vitamin D seems like a pretty nifty trick right? Why then are nearly 50 percent of us deficient in vitamin D?

Vitamin D Deficiency - Are YOU at Risk?

First, a little history lesson. Way back in the early 1600’s, the world was undergoing an industrial revolution. People were beginning to live in large cities, with housing being built close together and pollution from coal burning creating a haze in the air. It was around this time that a disease called Rickets began appearing in children. Rickets is a bone deforming disease that we now know is caused by a Vitamin D deficiency. The connection between the lack of sun exposure and Rickets was probably first made in the 1800’s by Polish physician Jedrzej Sniadecki.(1) He noticed that children in populated areas such as Warsaw, receiving little sunlight due to narrow alleyways, pollution and tight living quarters, had a higher incidence of rickets that those living in rural areas outside of Warsaw. In response to this observation, Sniadecki recommended in his book, On the Physical Education of Children (1822), that children “should be carried about in the open air especially in the sun, the direct action of which on our bodies must be regarded as one of the most efficient methods for the prevention and the cure of this disease.”(2)

Although most of Vitamin D’s fame comes from it’s role in aiding in the absorption of calcium and creating healthy bones, it is actually involved in a large number of important functions in our bodies. It plays a role in both immune function and control of inflammation. Therefore, it may be crucial in the management of both autoimmune and inflammatory diseases. It helps to regulate the release of a neurotransmitter called serotonin, which is important for both mental health and digestion. It is essential for healing, as it helps control cell growth. Vitamin D’s control over cell proliferation, along with its anti-inflammatory effects may have protective effects against many cancers. Scientists continue to study Vitamin D and its benefits to our health. The role of Vitamin D deficiency in heart disease, mental health, obesity and Parkinson’s disease are just a few of the many areas being studied.

So back to the original question – why are over 50 percent of us deficient in this important nutrient? The obvious answer is that we are not getting enough sunshine! There is a reason it is called the “Sunshine Vitamin”! Along with living at a higher latitude, our jobs and hobbies (I’m looking at you Netflix) are keeping us out of the sunshine. When we do venture out, we slather on the sunscreen, afraid of skin cancer and (yikes!) wrinkles. It is also difficult to get anywhere near enough Vitamin D from the food we eat. It can be found in the oil of fish livers (think cod liver oil) and there is a small amount in egg yolks and fatty fish, like salmon, sardines and mackerel. Plant foods, like mushrooms and leafy greens, contain a very small amount of Vitamin D2. It is thought, however, that this plant derived from of vitamin D doesn’t seem to perform all the functions that animal derived D3 does. Many foods, such as homogenized milk and breakfasts cereals are fortified with Vitamin D. Even if you aren’t avoiding these processed and packaged foods, in order to get your daily requirement of Vitamin D, you would have to consume an unfeasible amount of these foods! 

So Who is at risk?

  • Digestive Issues – Even if we could consume enough vitamin D in our diets, we are assuming that it is all going to be absorbed. The health of your gut is going to influence how much of the vitamin you absorb and, let’s face it, many of us have at least some digestive issues. Issues like celiac disease, Crohn’s disease, disorders (or absence) of the gallbladder can all reduce vitamin D absorption. These efficacy of vitamin D supplements are also affected by these digestive issues.
  • Obesity – Vitamin D is a fat soluble vitamin and is stored in fat tissue. Obesity means we have more fat in which to store that Vitamin D, making it less easily accessible when needed.
  • Darker skin tones – Higher amounts of the pigment melanin in dark skin tones acts as a natural sunscreen, reducing the amount of Vitamin D produced
  • Increased Age – Lower amounts of the precursor to Vitamin D, skin changes and more time spent indoors increases the risk of deficiency in older individuals
  • Time of year and location – UVB rays are weaker in the northern latitudes, so weak in fact that there are large periods of the year (4 to 6 months) when one just can’t make enough Vitamin D from sun exposure alone. (3)

How do I know if I’m deficient?

The symptoms of Vitamin D deficiency are often so subtle that you have no idea you are deficient. I know that I had no clue, until my blood test came back! The effects of vitamin D deficiency are varied and we rarely make the connection between these signals and a lack of vitamin D. They may include: 

  • Fatigue
  • Bone pain
  • Muscle or Joint pain
  • Frequent Illness
  • Low mood or irritability
  • Anxiety

So what can you do?

Advocate

Ask your physician for a blood test. Vitamin D levels are not something that most physicians will order with your yearly bloodwork. Because there are no overt signs of deficiency, I think it is important to know what you level is – especially if you fall into one of the groups who are more at risk for a deficiency. 

Conventional “normal” ranges can vary depending on the lab conducting the test.  They are also based on the average population which, if we are being honest, is not all that healthy. Generally, the “normal” range will be quite wide (30ng/ml to 100ng/ml). But this normal range doesn’t necessarily reflect what is healthy, only what is common. Functional references ranges are narrower and reflect a level that is optimal to prevent dysfunction and, eventually, disease. A functional optimal range for vitamin D is much narrower, perhaps at 60ng/ml to 80ng/ml. When disease is present, such as with heart disease or cancer, the optimal range may be higher.

Supplement

Most of us living in northern latitudes are not going to be able to get all the vitamin D we need year round. A high quality supplement can help us keep our levels up throughout the year. 

The amount of vitamin D to supplement will vary depending on your current blood level, health status and sun exposure. As always, it is important to have a discussion with your health care provider to determine an appropriate dose and have your levels monitored periodically. Also, always…ALWAYS consult your doctor or pharmacist before starting any supplementation, in order to rule out drug interactions or contraindications!

As vitamin D is fat soluble, there is a risk (although extremely small) of toxicity, because excess can be stored in the body. It is generally only seen in those who take extremely high doses for long periods of time. 

Sunlight

Overall, sun exposure really is the best source of vitamin D, as we don’t have to rely on adequate digestion for it to reach our bloodstream and get to work! It is a bit of a balancing act, especially if you are like me and go from bright white to lobster red in the blink of an eye. A general rule of thumb is for the time of sun exposure to be 50% of what it would take to cause a mild sunburn (slight pinkness 24 hours later). After this time, slather on the safe sunscreen, cover up or seek shade.(1) For me, that’s probably about 5 minutes in the mid-day summer sun! The more skin that is exposed, the more vitamin D those factories in your skin will produce. I would recommend protecting the face with sunscreen or a hat, as it’s surface area is relatively small and will produce only a small amount of vitamin D and the skin there is more prone to damage from sun exposure.

The other benefit of getting Vitamin D from the sun? Toxicity is not an issue. There are compounds made along with the Vitamin D that will limit any excess production, protecting us from toxicity. The body is a wondrous thing, isn’t it?

References

  1. Wacker, M., & Holick, M. F. (2013). Sunlight and Vitamin D: A global perspective for health. Dermato-endocrinology5(1), 51–108. https://doi.org/10.4161/derm.24494
  2. Mozołowski W. Jędrzej Sniadecki (1768-1838) on the Cure of Rickets. Nature. 1939;143:121. doi: 10.1038/143121a0
  3. https://academic.oup.com/ajcn/article/79/3/362/4690120(Holick MF. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr. 2004; 79:362-71)

The Monday Mention – Why Stomach Acid Is Good For You by Jonathan V. Wright M.D. and Lane Lenard, Ph.D

The Monday Mention - Why Stomach Acid is Good for You

I’ve been lucky, I think I’ve only ever experienced heartburn once in my life. It woke me from a deep sleep and had me frantically digging through my kitchen cupboards at 3am, looking for some sort of relief. We aren’t milk drinkers, so I couldn’t try that old remedy. I had a surprisingly empty medicine cabinet for a pharmacist, only some first aid cream and bandages. No Tums, no Gaviscon, no aBISMALly pink Pepto-Bismal. I decided to use my half awake, “sciency” brain and tackle the acid with its known nemesis – a base. Baking soda to the rescue. I mixed it with some water and took it like a shot. It was, well, it was awful.  Not something I’d want to have to do regularly. It took a little time, but the fire finally subsided enough for me to crawl back into bed, bedside my blissfully unaware husband, praying that the inferno wouldn’t return.

For many people, the discomfort of heartburn, indigestion or reflux is a daily occurrence. Just walk through the stomach section of any pharmacy and you’ll see just how prevalent these issues are. In my years in the pharmacy, prescriptions for acid reflux medications flew off the shelves. It was an equal opportunity Rx too! Men, women, young and old. Everyone needed their “stomach pills”. But just because these tummy troubles are common, does not mean they are normal. Instead, they are a sign that there is something amiss and your body is letting you know that all is NOT normal.

Why are there so many “fire breathers” around these days? Why do so many people produce such vast quantities of stomach acid that they need to be on a medication to control it? The truth is, they don’t. Over-production of stomach acid is a very rare condition (Zollinger-Ellison Syndrome) and it only affects about 1 in 1 million people.  There can be a couple of factors at play here. One is that certain dietary and lifestyle habits can relax the Lower Esophageal Sphincter (LES). The LES is the gateway between the esophagus and the stomach and it is meant to stay tightly closed to prevent stomach acid from coming into contact with the unprotected tissue of the esophagus. When you only experience symptoms once in awhile, simply changing some habits and avoiding those foods that trigger your symptoms will often suffice. 

The most common cause though, the ROOT cause, of these symptoms is actually insufficient stomach acid. Yes, wrap your brain around that. The current recommended remedies for heartburn and indigestion not only fail to treat the cause of the symptoms, but contribute to them and many more problems. This is the concept behind the book Why Stomach Acid Is Good For You by Johnathan V. Wright M.D. and Lane Lenard Ph.D. 

Wright and Lane propose that it is a lack of stomach acid that causes heartburn, indigestion and GERD and to properly treat the cause, the acid must be replaced. Drugs prescribed for these conditions turn off production and decrease stomach acid even further. They appear to help because they cover up the symptoms (your body’s way of messaging you that something is wrong), but they are actually potentiating the problem. So why is low stomach acid a bad thing, if it makes us feels so much better? 

Stomach acid plays a vital role in digestion. One of the key components of the gastric juices is HCl (hydrochloric acid). HCl is necessary to break proteins down into amino acids, which can then be absorbed. Many other nutrients require an acidic environment for absorption as well. Stomach acid is also the starter pistol or trigger for almost every other event in the digestive sequence. Without stomach acid, digestion functions about as well as car on empty.

The acidity of the gastric juices makes the stomach a sterile environment. Stomach acid kills pathogens that we ingest with our food. As well as protecting us from infection, this acidic environment prevents bacteria from surviving in the stomach and interfering with the digestion of certain nutrients. The negative consequences of low stomach acid continue to affect our digestion all the way down the line. I discuss the consequences (ad nauseam) in THIS blog post, if you want to get into the nitty gritty!

I found it interesting to learn that the cells that produce HCl (parietal cells) decrease as we age. Much of the malnutrition we see in senior citizens maybe caused by low stomach acid and treatable with acid supplementation. The authors discuss how nutrient deficiencies caused by low stomach acid may contribute to several conditions from depression all the way to rosacea. Besides nutrient deficiences, the book also looks at how low stomach acid leads to large, undigested protein molecules. These can make their way through the lining of the small intestine (made “leaky” by the damage of bacteria growing in the low acidic environment of the stomach). These large food molecules enter the bloodstream. They are not broken down enough to be recognized by the immune system, are tagged as foreign and attacked. Overtime, this immune system activation can cause food sensitivities and contribute to the development of autoimmune conditions.

Although I did find the authors somewhat wordy and repetitive, there was a lot of good information in this book. The link between low stomach acid and the myriad of problems it may contribute to makes common sense, even if there are few quality studies to support some of these claims. (I mean, a drug company is not likely to fund a study that may show their product is unnecessary at best and harmful at worst!)  As it was published in 2001, it would be nice if there were a newer edition of the book to highlight any current information in this area. I don’t know that I can agree wholeheartedly with some of the authors’ ideas that low stomach acid may be the out right cause of certain diseases. I certainly can agree that it could be a contributing factor and, as such, it is prudent to optimize stomach acid and digestion in all conditions. 

Do you have signs of low stomach acid? Work with a Functional Nutritional Therapy Practitioner to learn how to better support your digestion!

Please note, that if you are currently on a medication that lowers stomach acid, I am NOT recommending that you stop this treatment. Seek out a Functional Nutritional Therapy Practitioner (like moi), who can help you make some dietary and lifestyle changes that support digestion. Once those are in place, you can talk to your physician (or ideally your FNTP and physician can work together!) to discuss whether you need the medication, create a plan to wean off the medication and possibly start some acid supplementation, if needed, all while monitoring your symptoms.

Rating 3.5 Peaks
My Rating 3.5/5 Peaks